Precision therapeutics for fibrotic disease

Our Science

At Forth Therapeutics, we're pioneering precision therapeutics that target the underlying mechanisms driving fibrosis. Building on world-renowned research from Professor Neil Henderson at the University of Edinburgh, we leverage multi-omic insights from patient-derived tissue samples to develop potent, new therapies for patients.

Novel Approach to Fibrotic Disease

We combine cutting-edge single cell and spatial genomics approaches to identify antifibrotic targets with high precision. By focusing on specific markers of pathogenic cells, we're able to develop targeted interventions to halt and potentially reverse the course of fibrotic disease.

Fibrotic disease mechanism

Unparalleled data access

Our platform combines high-resolution mapping of the fibrotic niche with one of the largest single-cell human liver disease datasets in the world. Using advanced computational models and machine learning algorithms, we integrate data from multiple single cell and spatial genomics platforms to create a high-definition map of fibrotic disease, thereby accelerating precision drug discovery and development.

Data visualization

Our Therapies

Our portfolio includes three assets targeting key fibrosis pathways, underpinned by state-of-the-art omics technology. We believe our technology has broad applicability across fibrotic diseases. We will be announcing further details for our therapeutic development pipeline in Q4 2025.

pipeline

Leadership

Alex Leech, MBA

Alex Leech MBA

Chief Executive Officer

Neil Henderson, MD PhD FMedSci

Neil Henderson MD PhD FMedSci

Chief Scientific Officer

Ralph Minter, PhD

Ralph Minter PhD

Chief Technology Officer

Careers

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Contact Us

Have questions about our work or want to discuss potential partnerships? Please get in touch.

Our Locations

London1 Pancras Square, C/O Sofinnova Partners, London, England, N1C 4AG
Cambridge260 Meditrina, Babraham Research Campus, Cambridge, CB22 3AT
EdinburghRoom 2.43, Institute for Repair & Regeneration, 4-5 Little France Dr, Edinburgh, EH16 4UU